abstract：BACKGROUND AND OBJECTIVE:Chronic obstructive pulmonary disease (COPD) is characterized by chronic incompletely reversible poor airflow and air trapping and usually this debilitating disorder limits the outside activities of the patients depriving them of sunlight which is a rich source of Vitamin D. The objective of th...

journal_title：Pakistan journal of medical sciences

authors： Khan DM,Ullah A,Randhawa FA,Iqtadar S,Butt NF,Waheed K

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To determine the clinical presentation, diagnostic investigations and laboratory workup done in admitted children with cystic fibrosis at Aga Khan University Hospital Karachi, Pakistan. METHODS:This is athree years retrospective study from January 2013 to December 2015 conducted at The Aga Khan University Ho...

journal_title：Pakistan journal of medical sciences

authors： Aziz DA,Billoo AG,Qureshi A,Khalid M,Kirmani S

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Ectopic pregnancy in the interstitial part of the Fallopian tubes can be life-threatining considering the thin myometrial tissue surrounding the gestational sac and highly vascularization which may result in catastrophic haemorrhage when interstitium is ruptured. The diagnosis and management is challenging. C...

journal_title：Pakistan journal of medical sciences

authors： Kahramanoglu I,Mammadov Z,Turan H,Urer A,Tuten A

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To describe the frequency of color vision deficiency among Pakistani adults presenting for pre-employment health screening in a tertiary care hospital. METHODS:The cross-sectional study was carried out at the Aga Khan University Hospital, Karachi, and the data was collected for color vision deficiency, age, ...

journal_title：Pakistan journal of medical sciences

authors： Chhipa SA,Hashmi FK,Ali S,Kamal M,Ahmad K

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To determine the patient safety culture perception of operating room and intensive care nurses and the factors affecting this perception. METHODS:This descriptive study was conducted on 232 nurses working in a Turkish city hospitals. The data obtained from the nurses were collected using personal information...

journal_title：Pakistan journal of medical sciences

authors： Rizalar S,Topcu SY

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Helicobacter pylori (H. pylori) infection is cause of several gastrointestinal diseases in humans. Virulence genes of H. pylori are associated with severity of disease and vary geographically. The aim of present study was to detect H. pylori in formalin-fixed paraffin-embedded (FFPE) tissues a...

journal_title：Pakistan journal of medical sciences

authors： Bibi F,Alvi SA,Sawan SA,Yasir M,Sawan A,Jiman-Fatani AA,Azhar EI

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence, predictors, triggers and educational outcome of migraine among medical students and interns in King Abdulaziz University, Jeddah, Saudi Arabia. METHODS:A cross-sectional study was completed among 566 participants selected through a multistage stratified random sample method. A v...

journal_title：Pakistan journal of medical sciences

authors： Ibrahim NK,Alotaibi AK,Alhazmi AM,Alshehri RZ,Saimaldaher RN,Murad MA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND & OBJECTIVE:Rehabilitation focuses brain-behavior relationship which highlights interaction between psychological and neurobiological factors for better patient care. There is a missing link in the literature about socio-cognitive aspects of frontal lobe epilepsy. Our objective was to examine prefrontal cort...

journal_title：Pakistan journal of medical sciences

authors： Gul A,Ahmad H

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To observe the fetomaternal morbidity and mortality with induction of labour in pregnant women with gestational hypertension. METHODS:The subjected study population included was 138 pregnant women with gestational hypertension. These pregnant women were between 34-40 weeks of gestational period in whom labou...

journal_title：Pakistan journal of medical sciences

authors： Khaskheli MN,Baloch S,Sheeba A,Baloch S,Khan F

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Hyperlipidemia and dyslipidemia are very common conditions among patients with Type-2 diabetes mellitus (T2DM) and associated with increased risk of coronary heart diseases. Physical activity and exercises along with medical management and dietary plan are common strategies to use for the manag...

journal_title：Pakistan journal of medical sciences

authors： Shakil-Ur-Rehman S,Karimi H,Gillani SA

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of intercostal nerve protection by intercostal muscle (ICM) flap in post-thoracotomy pain improvement compared to intracostal suturing. METHODS:In a randomized controlled trial, ninety-four patients undergoing posterolateral thoracotomy surgery were divided into two subgroups. Intracos...

journal_title：Pakistan journal of medical sciences

authors： Montazer M,Hashemzade S,Gargari RM,Ramouz A,Sanaie S,Rasihashemi SZ

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To determine the risk factors of obesity and diet on breast cancer in Ankara, Turkey. METHODS:A case-controlled study was carried out on newly diagnosed 40 breast cancer patients [patient group (PC)] and 40 volunteer individuals [control group (CG)] with no diagnosis of cancer and history of cancer in the fa...

journal_title：Pakistan journal of medical sciences

authors： Alim NE,Kiziltan G

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To determine the role of serum procalcitonin (PCT) and C-reactive protein (CRP) in predicting spontaneous bacterial peritonitis (SBP) in patients with advanced liver cirrhosis. METHODS:A total of 88 patients with advanced liver cirrhosis were enrolled for this study, which included 40 cases with SBP and 48 c...

journal_title：Pakistan journal of medical sciences

authors： Wu H,Chen L,Sun Y,Meng C,Hou W

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To explore the effects of letrozole (LE) in combination with low-dose intramuscular injection of human menopausal gonadotropin (HMG) on the ovulation induction and pregnancy of patients with polycystic ovary syndrome (PCOS). METHODS:A total of 156 patients with PCOS infertility were randomly divided into an ...

journal_title：Pakistan journal of medical sciences

authors： Chen Z,Zhang M,Qiao Y,Yang J

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Genetic studies on gestational diabetes (GDM) are relatively scarce; moreover, limited data is available for KCNQ1 polymorphism in Pakistani pregnant women. We aimed to determine the frequency of KCNQ1 rs2237895 in GDM and normal pregnant controls and its association with GDM-related phenotypes...

journal_title：Pakistan journal of medical sciences

authors： Fatima SS,Chaudhry B,Khan TA,Farooq S

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Immunosuppressive drugs, antimicrobial agents and infectious complications may cause liver function test abnormalities (LFTA) in kidney transplant recipients (KTR). The objectives of this study were to identify the outcome of (LFTA). To identify the risk factors affecting development and severity of hepatotox...

journal_title：Pakistan journal of medical sciences

authors： Dizdar OS,Ersoy A,Aksoy S,Ozel Coskun BD,Yildiz A

更新日期：2016-11-01 00:00:00

abstract：:The objectives of Master of Philosophy (MPhil) in Physiological Sciences are: 1) to describe the new ways in which anatomy, biochemistry and physiology on one hand, and microbiology, pathology and pharmacology on other hand meet their functional requirements through multidisciplinary integrated concepts; 2) to elucida...

journal_title：Pakistan journal of medical sciences

authors： Ahmad HR,Arain FM,Khan NA

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To determine the association between serum 25 hydroxyvitamin D levels and percent breast density among asymptomatic premenopausal women. METHODS:Hundred asymptomatic, pre-menopausal women who visited the General Surgery Breast Clinic, Patel Hospital, Karachi, Pakistan between 3rd March and 10th November, 201...

journal_title：Pakistan journal of medical sciences

authors： Wasim B,Khan K,Samad MA

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:The present study aimed to assess the prevalence of decreased visual acuity, strabismus, and spectacle wear in children aged 5 to 13 years. METHODS:A cross-sectional study was performed in primary education schools. A total of 1938 participants, including 940 females (48.5%) and 998 males (51.5%) with a mean...

journal_title：Pakistan journal of medical sciences

authors： Ertekin YH,Tekin M,Uludag A,Arikan S,Sahin EM

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To observe clinical effects of three-dimensional conformal radiotherapy combined with Tegafur Gimeracil Oteracil Potassium chemotherapy in the treatment of patients with recurrent esophagus cancer. METHODS:One hundred and twelve senile patients who suffered from esophagus cancer were selected and randomly di...

journal_title：Pakistan journal of medical sciences

authors： Jiao Y,Shen Y,Yan H,Liu Y,Tan H,Li J

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Each year millions of Muslims perform pilgrimage to Makkah, Saudi Arabia. It is particularly stressful during the peak five days, when all rituals have to be performed at specific periods of time at different sites. Poor diabetes control in people with diabetes predisposes to morbidity and incr...

journal_title：Pakistan journal of medical sciences

authors： Hasan G,Moabber H,Alyamani A,Sayeed A,Altatar F

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To study the effect and clinical value of mammography in the diagnosis of breast lump so as to improve the diagnosis level of breast cancer. METHODS:A retrospective analysis was carried out on clinical data of 110 patients with mammary lump confirmed by pathology to study the compliance of mammography diagno...

journal_title：Pakistan journal of medical sciences

authors： Li H,Zhang S,Wang Q,Zhu R

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To isolate Helicobacter pylori (HP) from the dental plaque of a selected group of children and to compare the oral and salivary findings of patients with those of a healthy control group. METHODS:A total of 70 children aged 5-15 years were included in this study. An intraoral examination was performed for ea...

journal_title：Pakistan journal of medical sciences

authors： Dane A,Gurbuz T

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To document the neonatal outcomes of preterm birth in twin pregnancies and to investigate whether perinatal and obstetric parameters are associated with clinical outcomes. METHODS:This retrospective trial was conducted on data gathered from 176 preterm twins delivered in the obstetrics and gynecology departm...

journal_title：Pakistan journal of medical sciences

authors： Dolgun ZN,Inan C,Altintas AS,Okten SB,Sayin NC

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:The McGrath Video laryngoscope is a newly developed video laryngoscope that significantly improves laryngeal view and facilitates endotracheal intubation in difficult airways. However in patients with normal airway that is not mentioned before. The aim of this study was to compare the McGrath video laryngosco...

journal_title：Pakistan journal of medical sciences

authors： Sargin M,Uluer MS

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:Ventilator-associated pneumonia (VAP) is a significant cause of hospital-related infections, one that must be prevented due to its high morbidity and mortality. The purpose of this study was to evaluate the incidence and risk factors in patients developing VAP in our intensive care units (ICUs). METHODS:Thi...

journal_title：Pakistan journal of medical sciences

authors： Karatas M,Saylan S,Kostakoglu U,Yilmaz G

更新日期：2016-07-01 00:00:00

abstract：:MicroRNAs (miRs) are non-coding ribonucleic acids consisting of about 18-22 nucleotide bases. Expression of several miRs can be altered in breast carcinomas in comparison to healthy breast tissue, or between various subtypes of breast cancer. These are regulated as either oncogene or tumor suppressors, this shows that...

journal_title：Pakistan journal of medical sciences

authors： Usmani A,Shoro AA,Shirazi B,Memon Z

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Fentanyl is frequently used during anesthesia induction. The use of fentanyl can cause cough through different mechanisms. Here, we aimed to investigate effects of pheniramine maleate (PM), an antihistaminic agent, and compare it with lidocaine on fentanyl induced cough. METHODS:This is a randomized double-b...

journal_title：Pakistan journal of medical sciences

authors： Ozmen O,Kara D,Karaman EU,Karakoc F,Karakaya MA,Arslan Z

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To analyze the efficacies of tumor curettage and resection for treatment of giant cell tumor of the bone (GCTB) around the knee joint (KJ). METHODS:A total of 126 KJ-GCTB cases were treated at our department from August 2011 to February 2015. These cases were divided into two groups (A and B) according to tr...

journal_title：Pakistan journal of medical sciences

authors： Zhang S,Zhang J,Wang X

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To compare anti-albumin urea effects of Valsartan alone with combination of Valsartan and Amlodipine in patients of chronic kidney disease. METHODS:This randomized clinical trial was conducted at the Department of Medicine, Combined Military Hospital Bahawalpur, from April 2014 to 30 September 2014. 140 pati...

journal_title：Pakistan journal of medical sciences

authors： Ameen,Kashif MA,Sumreen

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the therapeutic effects in terms of disease clearance and hearing improvement of canal wall up mastoidectomy in combination with Type I tympanoplasty in otitis media. METHODS:A total of 78 patients (81 ears) with otitis media were treated by canal wall up mastoidectomy in combination with Type I ...

journal_title：Pakistan journal of medical sciences

authors： Zhang L

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:This meta-analysis was conducted to investigate the efficacy of bisphosphonates for preventing recurrent hip fracture and reducing the mortality of elderly patient with hip fracture. METHODS:The databases of Pubmed, Embase and Cochrane Library were searched. All randomized or prospective matched controlled t...

journal_title：Pakistan journal of medical sciences

authors： Peng J,Liu Y,Chen L,Peng K,Xu Z,Zhang D,Xiang Z

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence of dental caries, and associated social risk factors among preschool children in Riyadh, Saudi Arabia. METHODS:The study consisted of a random sample of 3 to 5 years- old preschool children who were examined in Riyadh, Saudi Arabia; 388 children (184 boys and 204 girls) were exam...

journal_title：Pakistan journal of medical sciences

authors： Al-Meedani LA,Al-Dlaigan YH

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between tea drinking habits and osteoporotic hip/femur fractures. METHODS:Paired case-control method was used for face-to-face interviews from January 2010 to June 2014. Patients (n=435) with newly osteoporotic hip/femur fracture and 435 controls with the same gender and age (±3) ...

journal_title：Pakistan journal of medical sciences

authors： Huang C,Tang R

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To identify what educational resources are used by medical students for their personal study during Primary health care (PHC) clinical rotation and the reasons for making these choices at King Saud University in Riyadh, Saudi Arabia. METHODS:A survey of 176 male and female medical students was conducted duri...

journal_title：Pakistan journal of medical sciences

authors： Al-Hazmi A

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To analyse the factors associated with Caesarean Section (CS) of Nulliparous, Term and Singleton pregnancies with Vertex presentation (NTSV) at a tertiary care hospital. METHODS:In this unmatched retrospective case-control study, 212 NTSV patients were identified through computerized medical record systems; ...

journal_title：Pakistan journal of medical sciences

authors： Ahmed I,Chishti U,Akhtar M,Ismail H

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the results of photorefractive keratectomy (PRK) with mitomycin C in myopia correction after five years. METHODS:This is a cross sectional study which included 145 eyes of 74 patients in 18 to 51 years age group that were undergoing Photorefractive keratectomy with mitomycin C using Allegretto Wa...

journal_title：Pakistan journal of medical sciences

authors： Hashemi M,Amiri MA,Tabatabaee M,Ayatollahi A

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To compare the effects of thoracotomy and total thoracoscopic surgery on coronary artery fistulae complicated with ectasia. METHODS:Forty-six patients with coronary artery fistulae complicated with ectasia were randomly divided into a treatment group and a control group (n=23) which were given totally thorac...

journal_title：Pakistan journal of medical sciences

authors： Sun H,Zhang L,Han X,Wang Z,Xu L

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To determine mean change in visual acuity, corneal astigmatism and clinical appearance of pterygium after intralesional injection of 5-Fluorouracil. METHODS:This was a Quasi experimental study conducted at Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan from June 2014 to May 2015. Total 68 eyes...

journal_title：Pakistan journal of medical sciences

authors： Khan MS,Malik S,Basit I

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To determine the current frequency and pattern of distribution of congenital heart defects (CHD) at National Institute of Cardiovascular Diseases (NICVD), with the age at which initial diagnosis of CHD was made and the age at which the participant first visited the study center. METHODS:This is a descriptive...

journal_title：Pakistan journal of medical sciences

authors： Pate N,Jawed S,Nigar N,Junaid F,Wadood AA,Abdullah F

更新日期：2016-01-01 00:00:00